脂肪的从头合成中的调控点和调控因子是什么

题目

脂肪的从头合成中的调控点和调控因子是什么
多谢啦 那个忘了一个 肉碱脂酰转移酶转移酶1的调控因子是啥 是贝塔氧化中的肉碱脂酰转移酶转移酶1的调控因子是啥 再次谢过

答案

乙酰辅酶A羧化酶
Acetyl CoA carboxylase plays a key role in regulating FA metabolism
which catalyzes committed step in FA synthesis,the production of malonyl CoA (activated two-carbon donor)
The carboxylase is controlled by 3 global signals (glucagon胰高血糖素,epineph-rine肾上腺素,and insulin胰岛素) that reflect overall needs of organism
Insulin stimulates FA synthesis by activating carboxylase
glucagon and epinephrine have reverse effect
Citrate activates the enzyme胰岛素和柠檬酸激活乙酰辅酶A羧化酶
Palmitoyl CoA and AMP lead to its inhibition
肾上腺素,胰高血糖素,棕榈酸,AMP等则抑制此酶.
尝试着看一下,这里很全